exRNAdisease

Entry Detail

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General Information

Database ID: exR0763111 RNA Name: RPL10 RNA Type: mRNA Chromosome: chrX Starnd: + Coordinate: Start Site(bp): 154389955 End Site(bp): 154409168 External Links: ENSG00000147403

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCD4 chr14 74285269 74303055 - ABRACL chr6 139028745 139043302 + AC004832.3 chr22 30409255 30428990 + AC006064.6 chr12 6556886 6607367 - AC010132.3 chr7 42909273 42932174 - AC010422.3 chr19 12643831 12648397 - AC011455.2 chr19 38915404 38949855 - AC048338.1 chr12 122207779 122266423 - AC055811.2 chr17 17202649 17237185 - ACO2 chr22 41469117 41528989 + ACTB chr7 5527148 5563784 - ADAL chr15 43330657 43354555 + ADAR chr1 154582057 154628013 - ADD3 chr10 109996368 110135565 + ADSL chr22 40346500 40390463 + AEN chr15 88621337 88632281 + AGBL5 chr2 27042364 27070622 + AHCY chr20 34280268 34311802 - AK2 chr1 33007940 33080996 - AKR7A2 chr1 19303965 19312146 - AL022238.4 chr22 40346529 40410054 + AL133352.1 chr10 100505628 100529881 - AL136295.5 chr14 24147548 24166452 + AL590764.2 chrX 71103987 71111575 - ALAS1 chr3 52198086 52214327 + ALDH16A1 chr19 49453225 49471050 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-6891-3p chr6 31355228 31355248 - hsa-miR-7847-3p chr11 1880105 1880125 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002550.2 chr16 19694035 19694428 - AC060766.7 chr17 35406684 35409768 - AC092490.1 chr12 8788253 8795789 + AL035446.1 chr6 140845958 140852924 - AL121992.1 chr1 15586136 15603626 - AL132780.1 chr14 22929607 22956374 + AL138828.1 chr6 135991936 136225751 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.