exRNAdisease

Entry Detail

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General Information

Database ID: exR0763118 RNA Name: RPL14 RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 40457292 End Site(bp): 40468587 External Links: ENSG00000188846

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCA1 chr9 104781006 104928155 - ABCB6 chr2 219209772 219218994 - AC010422.3 chr19 12643831 12648397 - AC068946.2 chr2 219209772 219222738 - AC105052.1 chr7 102582523 102642869 - AC105052.3 chr7 102637049 102671641 - AC126283.2 chr4 109713916 109801999 - AC245033.1 chr15 82536788 82573194 - ACAD9 chr3 128879596 128916067 + ACKR3 chr2 236567787 236582354 + ACLY chr17 41866917 41930542 - ACO2 chr22 41469117 41528989 + ACPP chr3 132317369 132368298 + ACSS1 chr20 25006230 25058980 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR1B chr2 97655939 97664044 - ACTR3 chr2 113890063 113962596 + ADAM33 chr20 3667965 3682246 - ADPGK chr15 72751369 72785846 - ADRM1 chr20 62302093 62308862 + AGO4 chr1 35808016 35857890 + AGPAT5 chr8 6708642 6761503 + AIF1L chr9 131096476 131123152 + AK4 chr1 65147549 65232145 + AL049629.2 chr11 33698261 33722467 - AL136454.1 chr1 192716132 192716653 + AL355987.3 chr9 136791379 136800595 + ALDH18A1 chr10 95605941 95656711 - ALDH1L2 chr12 105019784 105107643 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004943.2 chr16 72665123 72822781 + AC005540.1 chr2 190880797 190882059 - AC011468.5 chr19 52049007 52049754 + AC105383.1 chr4 133075311 133149147 - AC108010.1 chr7 128574751 128626473 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.