exRNAdisease

Entry Detail

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General Information

Database ID: exR0763123 RNA Name: RPL19 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 39200283 End Site(bp): 39204732 External Links: ENSG00000108298

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand A1BG chr19 58345178 58353492 - ABCA1 chr9 104781006 104928155 - ABCC4 chr13 95019835 95301475 - ABI2 chr2 203328239 203447728 + AC018523.2 chr11 14493783 14520344 - AC073508.2 chr17 40627356 40665141 - AC084337.2 chr11 6481485 6508978 + AC134669.1 chr17 31305213 31318831 - AC245033.1 chr15 82536788 82573194 - ACACA chr17 37084992 37406836 - ACLY chr17 41866917 41930542 - ACTG1 chr17 81509971 81523847 - ADAM10 chr15 58588809 58749791 - ADGRG6 chr6 142301854 142446266 + AGO2 chr8 140520156 140635633 - AHCY chr20 34280268 34311802 - AIMP2 chr7 6009255 6023834 + AL121753.1 chr20 35267885 35280043 - AL121758.1 chr20 646626 675800 - AL138752.2 chr9 37588413 38068687 - AL513165.2 chr9 37512547 37592469 - ALDH18A1 chr10 95605941 95656711 - ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006213.1 chr19 43996896 44003298 - AC012313.3 chr19 58346854 58362751 - AC023509.1 chr12 53441741 53467528 + AC113189.2 chr17 7420103 7444081 + AC113189.4 chr17 7439506 7445966 + AC245033.4 chr15 82533175 82540008 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.