exRNAdisease

Entry Detail

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General Information

Database ID: exR0763127 RNA Name: RPL23 RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 38847860 End Site(bp): 38853764 External Links: ENSG00000125691

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC245033.1 chr15 82536788 82573194 - AC007192.1 chr19 18153158 18178117 + ACSL4 chrX 109624244 109733403 - ADAMTS1 chr21 26835755 26845409 - AHCY chr20 34280268 34311802 - AK3 chr9 4709556 4742043 - AL928654.3 chr14 105487199 105492267 + AL139300.1 chr14 103562962 103685924 + ALDOA chr16 30064164 30070457 + ACTR2 chr2 65227753 65271253 + AC018512.1 chr15 43772617 43799133 - ADPGK chr15 72751369 72785846 - ACTG1 chr17 81509971 81523847 - AKR1B1 chr7 134442356 134459284 - AC068234.1 chr17 47253897 47344292 + AC010422.3 chr19 12643831 12648397 - AC073896.1 chr12 56285916 56316059 - AL713999.1 chr1 155169409 155187272 - AC040162.1 chr16 67929614 67936017 - ACIN1 chr14 23058564 23095614 - ACACA chr17 37084992 37406836 - ACTB chr7 5527148 5563784 - ADAM23 chr2 206443532 206621127 + AL121758.1 chr20 646626 675800 - AC124312.1 chr15 24955034 25000276 + AC120057.2 chr17 7240427 7244635 - ACO1 chr9 32384603 32454769 + ACTA1 chr1 229431245 229434098 - ALDH7A1 chr5 126531200 126595362 - ADD3 chr10 109996368 110135565 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4724-3p chr17 31534941 31534961 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005062.1 chr7 19918981 20140453 - AC005614.2 chr19 40048757 40090925 - AC007952.4 chr17 19112000 19112636 - AC009055.2 chr16 65190973 65234914 - AC016876.2 chr17 7581964 7584086 - AC023509.1 chr12 53441741 53467528 + AC090204.1 chr8 32927913 33045445 + AC091564.7 chr11 6610883 6616594 - AC092490.1 chr12 8788253 8795789 + AC120114.2 chr16 29862760 29863417 + AC132217.1 chr11 2129121 2129964 - AC135048.1 chr16 30948386 30956511 + AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL117332.1 chr20 21302731 21303704 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.