Entry Detail



General Information

Database ID:exR0763134
RNA Name:RPL28
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):55385345End Site(bp):55403250
External Links:ENSG00000108107



Disease Information

Disease Name:Glioblastoma Multiforme
Disease Category:Cancers
MeSH ID:D005909
Type:Neoplasms/Neoplasms, Glandular and Epithelial
Alias:Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell



Expression Detail

GEO ID:GSE106804
Description:Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:Cancer vs Control
Case Disease Type:Glioblastoma Multiforme
Case Disease SubType:NA
Case Sample:Glioblastoma Multiforme
Control Sample:Healthy
Number of Case:13
Number of Control:6
Number of Samples:19





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCD3
chr1
94418389
94518666
+
AC004832.3
chr22
30409255
30428990
+
AC004922.1
chr7
99325879
99394653
+
AC005258.1
chr19
2269525
2341172
+
AC006064.6
chr12
6556886
6607367
-
AC010323.1
chr19
8308283
8321379
-
AC010422.3
chr19
12643831
12648397
-
AC024592.3
chr19
5866171
5903787
-
AC073508.2
chr17
40627356
40665141
-
AC093525.2
chr16
2496032
2520218
+
AC104389.5
chr11
5254392
5678434
-
AC138811.2
chr16
18788063
18801519
-
ACAT2
chr6
159762045
159779112
+
ACLY
chr17
41866917
41930542
-
ACO2
chr22
41469117
41528989
+
ACTA1
chr1
229431245
229434098
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADGRL1
chr19
14147743
14206187
-
AEBP2
chr12
19404045
19720801
+
AGRN
chr1
1020120
1056118
+
AHCY
chr20
34280268
34311802
-
AKAP13
chr15
85380571
85749358
+
AL049629.2
chr11
33698261
33722467
-
AL669918.1
chr6
32813767
32838822
-
ALAS1
chr3
52198086
52214327
+
ALDH2
chr12
111766887
111817532
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-6805-5p
chr19
55388186
55388207
+
hsa-miR-6805-3p
chr19
55388220
55388242
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC010327.5
chr19
55216660
55221616
+
AC012360.3
chr2
105334027
105337475
-
AC016747.1
chr2
61141592
61144969
-
AC020928.2
chr19
36773712
36775908
-
AC026362.1
chr12
122975320
122982907
+
AC026471.1
chr16
31456711
31459736
-
AC091564.7
chr11
6610883
6616594
-
AC139149.1
chr17
81514047
81527776
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:29330365
Title:Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:Nat Commun. 2018 Jan 12;9(1):175.
Description:Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.