exRNAdisease

Entry Detail

---



General Information

Database ID: exR0763153 RNA Name: RPL5 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 92832013 End Site(bp): 92841924 External Links: ENSG00000122406

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCB4 chr7 87401697 87480435 - AC004922.1 chr7 99325879 99394653 + AGTPBP1 chr9 85546539 85742029 - ACO1 chr9 32384603 32454769 + AL136454.1 chr1 192716132 192716653 + ALDH18A1 chr10 95605941 95656711 - ACTR3 chr2 113890063 113962596 + ADSL chr22 40346500 40390463 + AC073896.1 chr12 56285916 56316059 - AC015802.6 chr17 76563710 76570544 - AC091167.2 chr15 90249556 90272208 + AGK chr7 141551278 141655244 + ACIN1 chr14 23058564 23095614 - AGO1 chr1 35869808 35930532 + AASS chr7 122073549 122144255 - ABL1 chr9 130713016 130887675 + AL022238.4 chr22 40346529 40410054 + AL365273.2 chr10 95860548 95924844 + ACP6 chr1 147629652 147670524 - ACVR1B chr12 51951699 51997078 + ALDOA chr16 30064164 30070457 + ACTR2 chr2 65227753 65271253 + AGA chr4 177430774 177442437 - AK2 chr1 33007940 33080996 - AEN chr15 88621337 88632281 + ADNP2 chr18 80109262 80147523 + AC073612.1 chr12 71674204 71698968 + AL121594.1 chr14 35122549 35317474 + ACTB chr7 5527148 5563784 - AGRN chr1 1020120 1056118 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3654 chr7 133034860 133034878 - hsa-miR-4426 chr1 192716333 192716349 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010163.1 chr10 78293842 78301003 + AC018521.1 chr17 47945424 47981736 + AC022167.2 chr16 8848105 8860456 + AC024940.6 chr12 31280422 31280895 - AC104461.1 chr1 200333193 200478669 + AC132217.1 chr11 2129121 2129964 - AC139149.1 chr17 81514047 81527776 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.