exRNAdisease

Entry Detail

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General Information

Database ID: exR0763173 RNA Name: RPS11 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 49496365 End Site(bp): 49499708 External Links: ENSG00000142534

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC245033.1 chr15 82536788 82573194 - ADCY1 chr7 45574140 45723116 + ADAR chr1 154582057 154628013 - AK2 chr1 33007940 33080996 - ADGRL1 chr19 14147743 14206187 - ADH5 chr4 99070978 99088801 - AC131160.1 chr3 183815568 183884889 - AAGAB chr15 67200667 67255195 - ACTG1 chr17 81509971 81523847 - AL138752.2 chr9 37588413 38068687 - ABCE1 chr4 145098288 145129524 + AIP chr11 67483026 67491103 + AC010422.3 chr19 12643831 12648397 - AC099811.2 chr17 42119674 42154916 - AC079594.2 chr3 160227454 160449829 - AL603832.3 chr1 112702614 112711433 - ABHD18 chr4 127965306 128039927 + ADGRL2 chr1 81306160 81992436 + AC138811.2 chr16 18788063 18801519 - AKIRIN1 chr1 38991276 39006059 + AL162231.3 chr9 34646645 34657113 + ALDH18A1 chr10 95605941 95656711 - AC004922.1 chr7 99325879 99394653 + ACSS2 chr20 34872146 34927962 + AC007192.1 chr19 18153158 18178117 + AC005258.1 chr19 2269525 2341172 + ADAM10 chr15 58588809 58749791 - AFDN chr6 167826922 167972023 + AL133352.1 chr10 100505628 100529881 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-210-3p chr11 568112 568133 - hsa-miR-632 chr17 32350169 32350187 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004687.1 chr17 58330884 58332508 - AC010624.2 chr19 50075123 50075902 + AC108134.2 chr16 3156736 3157483 - AD000090.1 chr19 35557956 35581954 + AL117378.1 chr6 131901963 131920565 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.