exRNAdisease

Entry Detail

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General Information

Database ID: exR0763177 RNA Name: RPS15 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 1438358 End Site(bp): 1440494 External Links: ENSG00000115268

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD17A chr19 1876810 1885547 - AC004922.1 chr7 99325879 99394653 + AC010422.3 chr19 12643831 12648397 - AC011462.1 chr19 41350853 41425001 + AC099811.2 chr17 42119674 42154916 - AC124312.1 chr15 24955034 25000276 + ACOT13 chr6 24667035 24705065 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADO chr10 62804720 62808479 + AGPAT2 chr9 136673143 136687457 - AGPAT3 chr21 43865223 43987592 + AL136295.3 chr14 24120956 24131829 + AL139260.3 chr1 38864501 38881617 - AL928654.3 chr14 105487199 105492267 + ALDH5A1 chr6 24494867 24537207 + ALDH9A1 chr1 165662216 165698863 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-155-3p chr21 25574022 25574043 + hsa-miR-7847-3p chr11 1880105 1880125 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002116.1 chr19 36008638 36014235 - AC004687.1 chr17 58330884 58332508 - AC005083.1 chr7 20217577 20221700 + AC009065.2 chr16 2235689 2236913 - AC009133.5 chr16 29808679 29812227 + AC016876.2 chr17 7581964 7584086 - AC027307.3 chr19 1440839 1441938 + AC090114.2 chr7 128524016 128531069 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.