exRNAdisease

Entry Detail

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General Information

Database ID: exR0763180 RNA Name: RPS17 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 82536750 End Site(bp): 82540459 External Links: ENSG00000182774

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCA3 chr16 2275881 2340746 - AC004832.3 chr22 30409255 30428990 + AC007192.1 chr19 18153158 18178117 + AC011005.1 chr7 129126518 129130793 + AC011462.1 chr19 41350853 41425001 + AC020909.1 chr19 50415799 50428409 + AC024592.3 chr19 5866171 5903787 - AC025165.3 chr12 57772660 57797554 + AC245033.1 chr15 82536788 82573194 - ACAD9 chr3 128879596 128916067 + ACO2 chr22 41469117 41528989 + ACTB chr7 5527148 5563784 - ACTC1 chr15 34790230 34795549 - ACTN1 chr14 68874143 68979440 - ACTN4 chr19 38647649 38731589 + ACTR1A chr10 102461881 102502712 - ACTR3 chr2 113890063 113962596 + ADO chr10 62804720 62808479 + AHCYL1 chr1 109984765 110023742 + AK3 chr9 4709556 4742043 - AL110118.2 chr14 93184973 93218586 + AL121845.3 chr20 63708864 63739103 + AL132780.3 chr14 22946270 22982258 - AL133352.1 chr10 100505628 100529881 - AL590764.2 chrX 71103987 71111575 - AL603832.3 chr1 112702614 112711433 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-155-3p chr21 25574022 25574043 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC025181.2 chr5 32174471 32175272 + AC026304.1 chr3 143000907 143001467 - AC026362.1 chr12 122975320 122982907 + AC087482.1 chr15 66984103 67065268 - AC091564.7 chr11 6610883 6616594 - AC114763.1 chr2 138418284 138501698 - AC124312.5 chr15 25091786 25107469 - AC132217.1 chr11 2129121 2129964 - AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.