exRNAdisease

Entry Detail

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General Information

Database ID: exR0763182 RNA Name: RPS19 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 41860255 End Site(bp): 41872925 External Links: ENSG00000105372

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACADM chr1 75724347 75787575 + ALDOA chr16 30064164 30070457 + ACTG1 chr17 81509971 81523847 - ABCC5 chr3 183919934 184017939 - AL022238.4 chr22 40346529 40410054 + AC092143.1 chr16 89919165 89936092 + AHRR chr5 271670 438291 + ADD1 chr4 2843857 2930076 + ALDH7A1 chr5 126531200 126595362 - AL136295.4 chr14 24180395 24190416 - AC011511.1 chr19 10305427 10316009 - ADA chr20 44619522 44652233 - AIFM1 chrX 130129362 130165887 - AC087289.3 chr17 75898645 75930129 - ACAD9 chr3 128879596 128916067 + AL358113.1 chr9 69035747 69255187 + AKNA chr9 114334156 114394405 - AC005258.1 chr19 2269525 2341172 + AK1 chr9 127866486 127877675 - ABHD8 chr19 17292131 17310236 - AC010422.3 chr19 12643831 12648397 - AKT2 chr19 40230317 40285536 - AGFG1 chr2 227472152 227561214 + ACSS2 chr20 34872146 34927962 + AC026464.4 chr16 69299682 69322700 + ACOX1 chr17 75941507 75979177 - AGFG2 chr7 100539203 100568220 + ADH5 chr4 99070978 99088801 - AC120057.2 chr17 7240427 7244635 - AC048338.1 chr12 122207779 122266423 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-130b-5p chr22 21653316 21653336 + hsa-miR-4284 chr7 73711327 73711344 + hsa-miR-6797-3p chr19 41869675 41869696 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004687.1 chr17 58330884 58332508 - AC008033.3 chr12 68426331 68427737 - AC010327.5 chr19 55216660 55221616 + AC016876.2 chr17 7581964 7584086 - AC026304.1 chr3 143000907 143001467 - AC067930.1 chr8 143579636 143580670 + AC068338.2 chr15 75368155 75369584 + AC074135.1 chr19 23075201 23100361 + AC090204.1 chr8 32927913 33045445 + AC105036.3 chr15 75527150 75601205 - AC132217.1 chr11 2129121 2129964 - AC133540.1 chr16 85489813 85490831 + AC135048.1 chr16 30948386 30956511 + AC148477.2 chr12 132277349 132280900 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.