exRNAdisease

Entry Detail

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General Information

Database ID: exR0763187 RNA Name: RPS23 RNA Type: mRNA Chromosome: chr5 Starnd: - Coordinate: Start Site(bp): 82273320 End Site(bp): 82278396 External Links: ENSG00000186468

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AKIRIN2 chr6 87674860 87702233 - ABCA1 chr9 104781006 104928155 - AC105052.1 chr7 102582523 102642869 - AC137834.1 chr12 57249609 57296484 - ALDOA chr16 30064164 30070457 + ACTN4 chr19 38647649 38731589 + ACTR2 chr2 65227753 65271253 + ADNP chr20 50888916 50931437 - ABL1 chr9 130713016 130887675 + AL365205.1 chr6 41780349 41790141 + AIP chr11 67483026 67491103 + AL133352.1 chr10 100505628 100529881 - ACOT7 chr1 6264269 6394391 - ACAP2 chr3 195274745 195443044 - ADAR chr1 154582057 154628013 - AC118549.1 chr1 77562416 77683419 - AC005943.1 chr19 1578339 1605445 - ADA chr20 44619522 44652233 - ALDH7A1 chr5 126531200 126595362 - AFG3L2 chr18 12328944 12377227 - AL136295.1 chr14 24189157 24213473 - ADORA1 chr1 203090654 203167405 + ACTG1 chr17 81509971 81523847 - ABCE1 chr4 145098288 145129524 + AAGAB chr15 67200667 67255195 - ADARB1 chr21 45073853 45226560 + ACSS3 chr12 80936414 81261210 + ABHD8 chr19 17292131 17310236 - ABHD10 chr3 111979010 111993368 + ACTB chr7 5527148 5563784 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-19a-3p chr13 91350939 91350961 + hsa-miR-19b-3p chr13 91351245 91351267 + hsa-miR-135b-5p chr1 205448361 205448383 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007566.1 chr7 92457564 92495601 + AC010226.1 chr5 115602057 115623897 + AC010442.1 chr5 466124 473098 - AC012531.2 chr12 54017110 54035361 + AC016876.2 chr17 7581964 7584086 - AC023509.1 chr12 53441741 53467528 + AC026461.1 chr16 56682470 56687807 + AC064807.1 chr8 51899268 51949874 + AC079781.5 chr7 97851688 97972985 - AC099329.1 chr3 42785087 42852428 - AC126365.1 chr17 20788071 20789584 + AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + AL096870.2 chr14 24209646 24215987 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.