exRNAdisease

Entry Detail

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General Information

Database ID: exR0763189 RNA Name: RPS25 RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 119015712 End Site(bp): 119018691 External Links: ENSG00000118181

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABI2 chr2 203328239 203447728 + AC004922.1 chr7 99325879 99394653 + AC091167.2 chr15 90249556 90272208 + AC092647.5 chr7 55887277 55955239 + ACAD9 chr3 128879596 128916067 + ACSS3 chr12 80936414 81261210 + ACTA1 chr1 229431245 229434098 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADCK2 chr7 140672945 140696261 + ADCY3 chr2 24819169 24919839 - ADD1 chr4 2843857 2930076 + ADD3 chr10 109996368 110135565 + ADPRH chr3 119579268 119589945 + AFG3L2 chr18 12328944 12377227 - AGFG1 chr2 227472152 227561214 + AGK chr7 141551278 141655244 + AGPAT3 chr21 43865223 43987592 + AICDA chr12 8602170 8612867 - AKAP13 chr15 85380571 85749358 + AKAP17A chrX 1591604 1602520 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1248 chr3 186786675 186786701 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026362.1 chr12 122975320 122982907 + AC026464.2 chr16 69463844 69466264 + AC121761.2 chr12 75333798 75334486 - AC126365.1 chr17 20788071 20789584 + AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + AL021707.1 chr22 38739003 38749041 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.