exRNAdisease

Entry Detail

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General Information

Database ID: exR0763192 RNA Name: RPS27A RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 55231903 End Site(bp): 55235853 External Links: ENSG00000143947

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF2 chr7 151207837 151227166 - ABHD2 chr15 89087459 89202355 + ABRACL chr6 139028745 139043302 + AC068946.1 chr2 219075329 219170827 - AC091167.2 chr15 90249556 90272208 + AC245033.1 chr15 82536788 82573194 - ACAD8 chr11 134253495 134265855 + ACLY chr17 41866917 41930542 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR2 chr2 65227753 65271253 + ACVR1 chr2 157736444 157876330 - ADAR chr1 154582057 154628013 - ADD1 chr4 2843857 2930076 + ADORA2A chr22 24417879 24442357 + ADSL chr22 40346500 40390463 + AGAP1 chr2 235494043 236131800 + AGPAT4 chr6 161129967 161274061 - AGTPBP1 chr9 85546539 85742029 - AHNAK chr11 62433542 62556235 - AIF1L chr9 131096476 131123152 + AL022238.4 chr22 40346529 40410054 + AL133352.1 chr10 100505628 100529881 - AL136454.1 chr1 192716132 192716653 + AL139300.1 chr14 103562962 103685924 + AL355315.1 chr10 97584374 97673910 + ALDH7A1 chr5 126531200 126595362 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4426 chr1 192716333 192716349 + hsa-miR-4485-3p chr11 10508277 10508296 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC091564.7 chr11 6610883 6616594 - AC104257.1 chr8 131308545 131317632 + AC106864.1 chr4 112693047 112706810 - AC239868.1 chr1 149861271 149862504 + AC245033.4 chr15 82533175 82540008 - AL031656.1 chr20 42685404 42688562 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.