exRNAdisease

Entry Detail

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General Information

Database ID: exR0763215 RNA Name: RPSA RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 39406716 End Site(bp): 39412542 External Links: ENSG00000168028

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD12 chr20 25294742 25390835 - ABHD2 chr15 89087459 89202355 + AC008575.1 chr5 112827213 112867582 + AC018523.2 chr11 14493783 14520344 - AC104109.3 chr5 134167170 134226071 - ACACA chr17 37084992 37406836 - ACSL6 chr5 131949973 132012243 - ACTA2 chr10 88935074 88991339 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - AFF4 chr5 132875395 132963634 - AGFG1 chr2 227472152 227561214 + AHCY chr20 34280268 34311802 - AL355987.3 chr9 136791379 136800595 + ALDH7A1 chr5 126531200 126595362 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004687.1 chr17 58330884 58332508 - AC005618.1 chr5 141326210 141329357 + AC005899.4 chr17 32328441 32329395 + AC006064.5 chr12 6510275 6510522 + AC016876.2 chr17 7581964 7584086 - AC019205.1 chr6 73263212 73301789 + AC023509.1 chr12 53441741 53467528 + AC068205.2 chr11 43578889 43840030 + AC087190.3 chr16 9104848 9113181 + AC091564.7 chr11 6610883 6616594 - AC124312.3 chr15 25087661 25088896 + AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.