exRNAdisease

Entry Detail

---



General Information

Database ID: exR0763262 RNA Name: RTN3 RNA Type: mRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 63681446 End Site(bp): 63759891 External Links: ENSG00000133318

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAGAB chr15 67200667 67255195 - ABCA3 chr16 2275881 2340746 - AC007192.1 chr19 18153158 18178117 + AC034102.2 chr12 56101331 56109289 + AC068946.2 chr2 219209772 219222738 - AC073508.2 chr17 40627356 40665141 - AC093525.1 chr16 2513965 2527955 + AC110275.1 chr8 43018424 43077334 + AC245033.1 chr15 82536788 82573194 - ACBD5 chr10 27195214 27242130 - ACTR2 chr2 65227753 65271253 + ADGRG6 chr6 142301854 142446266 + AGK chr7 141551278 141655244 + AHCTF1 chr1 246839098 246931967 - AKR1B1 chr7 134442356 134459284 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-185-5p chr22 20033153 20033174 + hsa-miR-1321 chrX 85835832 85835849 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005332.5 chr17 68133201 68135935 + AC104461.1 chr1 200333193 200478669 + AC125807.2 chr12 3041437 3044950 + AC245033.4 chr15 82533175 82540008 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.