exRNAdisease

Entry Detail

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General Information

Database ID: exR0763364 RNA Name: SCD RNA Type: mRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 100347233 End Site(bp): 100364826 External Links: ENSG00000099194

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010132.3 chr7 42909273 42932174 - AC018523.2 chr11 14493783 14520344 - AC048338.1 chr12 122207779 122266423 - AC092143.1 chr16 89919165 89936092 + AC120057.2 chr17 7240427 7244635 - AC138811.2 chr16 18788063 18801519 - ACP1 chr2 264140 278283 + ACP6 chr1 147629652 147670524 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR2 chr2 65227753 65271253 + ADAR chr1 154582057 154628013 - ADSL chr22 40346500 40390463 + AEBP2 chr12 19404045 19720801 + AGBL5 chr2 27042364 27070622 + AGPS chr2 177392757 177559299 + AIG1 chr6 143060496 143341058 + AKIRIN2 chr6 87674860 87702233 - AL022238.4 chr22 40346529 40410054 + ALDH7A1 chr5 126531200 126595362 - ALDH9A1 chr1 165662216 165698863 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-7-5p chr19 4770700 4770723 + hsa-miR-185-5p chr22 20033153 20033174 + hsa-miR-1321 chrX 85835832 85835849 + hsa-miR-1197 chr14 101025620 101025640 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004816.1 chr14 70809841 70815994 + AC005618.1 chr5 141326210 141329357 + AC009446.1 chr8 71675300 71702786 + AC010719.1 chr7 25948657 25949403 - AC106795.2 chr5 177950335 177963960 + AC106864.1 chr4 112693047 112706810 - AC124068.2 chr15 89335053 89336161 + AC124283.3 chr17 82578023 82578616 + AC126365.1 chr17 20788071 20789584 + AL132780.1 chr14 22929607 22956374 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.