exRNAdisease

Entry Detail

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General Information

Database ID: exR0763517 RNA Name: SET RNA Type: mRNA Chromosome: chr9 Starnd: + Coordinate: Start Site(bp): 128683424 End Site(bp): 128696400 External Links: ENSG00000119335

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + ABCB8 chr7 151028422 151047782 + ABCC6 chr16 16148928 16223522 - AC007846.2 chr17 5772926 6080792 + AC010463.1 chr19 17267418 17282966 + AC012254.2 chr18 47108188 47176345 - AC138811.2 chr16 18788063 18801519 - ACACA chr17 37084992 37406836 - ACBD3 chr1 226144679 226186741 - ACTB chr7 5527148 5563784 - ACTN4 chr19 38647649 38731589 + ADM chr11 10305073 10307397 + AGO3 chr1 35930718 36072500 + AHCYL1 chr1 109984765 110023742 + AKAP12 chr6 151239967 151358559 + AL139011.2 chr1 160216800 160285130 - AL590132.1 chr1 210858125 211134146 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3648 chr21 8987026 8987046 + hsa-miR-6728-3p chr1 8866502 8866522 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC023509.1 chr12 53441741 53467528 + AC124068.2 chr15 89335053 89336161 + AL121985.1 chr1 160670778 160699761 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.