exRNAdisease

Entry Detail

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General Information

Database ID: exR0763530 RNA Name: SF1 RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 64764606 End Site(bp): 64778786 External Links: ENSG00000168066

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + AC005258.1 chr19 2269525 2341172 + AC008750.8 chr19 51350373 51368099 - AC008878.3 chr19 7382834 7470241 + AC011005.1 chr7 129126518 129130793 + AC015813.2 chr17 57989038 58007246 - AC245033.1 chr15 82536788 82573194 - ACAD9 chr3 128879596 128916067 + ACTB chr7 5527148 5563784 - ACTR2 chr2 65227753 65271253 + AKR1B1 chr7 134442356 134459284 - AL031708.1 chr16 1632259 1686715 + ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC012321.1 chr16 69703065 69704652 + AC022336.2 chr3 124723788 124726325 + AD000090.1 chr19 35557956 35581954 + AL121992.1 chr1 15586136 15603626 - AL137127.1 chr1 19072110 19075511 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.