exRNAdisease

Entry Detail

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General Information

Database ID: exR0763543 RNA Name: SFPQ RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 35176378 End Site(bp): 35193145 External Links: ENSG00000116560

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAAS chr12 53307456 53324864 - ABLIM1 chr10 114431113 114768061 - AC008982.1 chr19 38817471 38840178 - AC010422.3 chr19 12643831 12648397 - AC091551.1 chr18 50968019 51058144 + AC105052.3 chr7 102637049 102671641 - AC118553.2 chr1 99970011 100083321 + ACSS1 chr20 25006230 25058980 - ACTR2 chr2 65227753 65271253 + ADAMTSL4 chr1 150549369 150560937 + ADGRA3 chr4 22345071 22516066 - ADORA2A chr22 24417879 24442357 + AGO4 chr1 35808016 35857890 + AHCY chr20 34280268 34311802 - AKR1A1 chr1 45550543 45570049 + AL117339.5 chr10 38094368 38360098 + AL136295.5 chr14 24147548 24166452 + AL365205.1 chr6 41780349 41790141 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-205-5p chr1 209432166 209432187 + hsa-miR-3652 chr12 103930425 103930442 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006504.5 chr19 27793431 27984984 + AC067930.1 chr8 143579636 143580670 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.