exRNAdisease

Entry Detail

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General Information

Database ID: exR0763602 RNA Name: SHMT2 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 57229573 End Site(bp): 57234935 External Links: ENSG00000182199

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + ABCG2 chr4 88090150 88231628 - AC004922.1 chr7 99325879 99394653 + AC010132.3 chr7 42909273 42932174 - AC010422.3 chr19 12643831 12648397 - AC138811.2 chr16 18788063 18801519 - ACAT1 chr11 108116695 108147603 + ACER3 chr11 76860867 77026797 + ACTG1 chr17 81509971 81523847 - ACTN4 chr19 38647649 38731589 + ACTR2 chr2 65227753 65271253 + ADRM1 chr20 62302093 62308862 + AGRN chr1 1020120 1056118 + AKAP12 chr6 151239967 151358559 + AKNA chr9 114334156 114394405 - AL121594.1 chr14 35122549 35317474 + AL136454.1 chr1 192716132 192716653 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4426 chr1 192716333 192716349 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC091564.7 chr11 6610883 6616594 - AC106864.1 chr4 112693047 112706810 - AC132217.1 chr11 2129121 2129964 - AC133644.3 chr2 87455476 87767359 + AC137834.2 chr12 57229498 57230198 - AC139149.1 chr17 81514047 81527776 + AL136985.3 chr1 58715609 58771295 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.