exRNAdisease

Entry Detail

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General Information

Database ID: exR0763874 RNA Name: SMARCA4 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 10960825 End Site(bp): 11079426 External Links: ENSG00000127616

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABRACL chr6 139028745 139043302 + AC004922.1 chr7 99325879 99394653 + AC008982.1 chr19 38817471 38840178 - AC010422.3 chr19 12643831 12648397 - AC011511.4 chr19 10315471 10320678 - AC073508.2 chr17 40627356 40665141 - AC087289.3 chr17 75898645 75930129 - AC139530.2 chr17 81703371 81720539 + ACTG1 chr17 81509971 81523847 - ADAM19 chr5 157395534 157575775 - ADH5 chr4 99070978 99088801 - ADI1 chr2 3497366 3519531 - ADIPOR2 chr12 1688574 1788674 + ADNP chr20 50888916 50931437 - AFF1 chr4 86935002 87141054 + AL136295.1 chr14 24189157 24213473 - ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009902.2 chr8 81279871 81281446 - AC080013.1 chr3 158732263 158784070 + AD000090.1 chr19 35557956 35581954 + AL096870.2 chr14 24209646 24215987 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.