exRNAdisease

Entry Detail

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General Information

Database ID: exR0763878 RNA Name: SMARCB1 RNA Type: mRNA Chromosome: chr22 Starnd: + Coordinate: Start Site(bp): 23786931 End Site(bp): 23838008 External Links: ENSG00000099956

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005258.1 chr19 2269525 2341172 + AC093525.1 chr16 2513965 2527955 + ACAD8 chr11 134253495 134265855 + ACIN1 chr14 23058564 23095614 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTN1 chr14 68874143 68979440 - ADCY3 chr2 24819169 24919839 - ADD3 chr10 109996368 110135565 + ADGRL1 chr19 14147743 14206187 - ADSL chr22 40346500 40390463 + AHCY chr20 34280268 34311802 - AKIRIN1 chr1 38991276 39006059 + AL022238.4 chr22 40346529 40410054 + AL121845.3 chr20 63708864 63739103 + AL136454.1 chr1 192716132 192716653 + ALDH16A1 chr19 49453225 49471050 + ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008403.3 chr19 48547637 48597238 - AC016876.2 chr17 7581964 7584086 - AC019205.1 chr6 73263212 73301789 + AC079781.5 chr7 97851688 97972985 - AC132217.1 chr11 2129121 2129964 - AL035458.2 chr20 34234840 34281173 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.