exRNAdisease

Entry Detail

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General Information

Database ID: exR0763885 RNA Name: SMC1A RNA Type: mRNA Chromosome: chrX Starnd: - Coordinate: Start Site(bp): 53374149 End Site(bp): 53422728 External Links: ENSG00000072501

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007192.1 chr19 18153158 18178117 + AC010646.1 chr19 17235940 17255448 - AC040162.1 chr16 67929614 67936017 - ACTB chr7 5527148 5563784 - ACTN1 chr14 68874143 68979440 - AD000671.1 chr19 35745678 35754519 + ADIPOR1 chr1 202940826 202958572 - AFDN chr6 167826922 167972023 + AGAP6 chr10 49982190 50010499 + AHCY chr20 34280268 34311802 - AL162417.1 chr9 133098121 133163914 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-92a-3p chrX 134169544 134169565 - hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-34c-5p chr11 111513451 111513473 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC124068.2 chr15 89335053 89336161 + AD000090.1 chr19 35557956 35581954 + AL035458.2 chr20 34234840 34281173 - AL135925.1 chr10 79825902 79827602 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.