exRNAdisease

Entry Detail

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General Information

Database ID: exR0763955 RNA Name: SNRNP70 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 49085419 End Site(bp): 49108605 External Links: ENSG00000104852

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD11 chr7 73736094 73738867 - AC005943.1 chr19 1578339 1605445 - AC010422.3 chr19 12643831 12648397 - AC104581.2 chr17 7925931 7930622 - ACSL4 chrX 109624244 109733403 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADAMTS3 chr4 72280969 72569221 - AGRN chr1 1020120 1056118 + AHCY chr20 34280268 34311802 - AL359922.1 chr9 21802636 22029594 + ALDH18A1 chr10 95605941 95656711 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC007952.4 chr17 19112000 19112636 - AC010245.2 chr5 75608817 75609983 + AC012485.1 chr2 238231684 238255633 + AC012615.1 chr19 1874871 1876169 - AC025575.2 chr12 71047402 71118247 - AC108134.2 chr16 3156736 3157483 - AD000090.1 chr19 35557956 35581954 + AL136985.3 chr1 58715609 58771295 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.