exRNAdisease

Entry Detail

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General Information

Database ID: exR0763967 RNA Name: SNRPN RNA Type: mRNA Chromosome: chr15 Starnd: + Coordinate: Start Site(bp): 24823637 End Site(bp): 24978723 External Links: ENSG00000128739

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCC4 chr13 95019835 95301475 - ABRACL chr6 139028745 139043302 + AC006064.6 chr12 6556886 6607367 - AC012254.2 chr18 47108188 47176345 - AC068946.2 chr2 219209772 219222738 - AC124312.1 chr15 24955034 25000276 + AC137834.1 chr12 57249609 57296484 - ACTB chr7 5527148 5563784 - ACTN4 chr19 38647649 38731589 + ACTR1A chr10 102461881 102502712 - ACTR1B chr2 97655939 97664044 - ACVR1B chr12 51951699 51997078 + ACVR2B chr3 38453890 38493142 + AGO3 chr1 35930718 36072500 + AKAP17A chrX 1591604 1602520 + AL136454.1 chr1 192716132 192716653 + ALDH1B1 chr9 38392702 38398661 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012467.2 chr3 53858994 53861576 - AC067852.2 chr17 42552436 42554748 - AC092490.1 chr12 8788253 8795789 + AC106864.1 chr4 112693047 112706810 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.