exRNAdisease

Entry Detail

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General Information

Database ID: exR0764006 RNA Name: SON RNA Type: mRNA Chromosome: chr21 Starnd: + Coordinate: Start Site(bp): 33543038 End Site(bp): 33577481 External Links: ENSG00000159140

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACACA chr17 37084992 37406836 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADAMTS1 chr21 26835755 26845409 - ADNP2 chr18 80109262 80147523 + ADSL chr22 40346500 40390463 + AFDN chr6 167826922 167972023 + AHCY chr20 34280268 34311802 - AIFM1 chrX 130129362 130165887 - AKAP8L chr19 15380050 15419141 - AL022238.4 chr22 40346529 40410054 + AL136454.1 chr1 192716132 192716653 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-143-3p chr5 149428978 149428998 + hsa-miR-6501-5p chr21 33550664 33550685 + hsa-miR-6501-3p chr21 33550705 33550727 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC051619.7 chr15 45200325 45200632 - AC105036.3 chr15 75527150 75601205 - AC132217.1 chr11 2129121 2129964 - AL021368.3 chr6 57855891 57856468 - AL135999.1 chr14 23561097 23568073 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.