exRNAdisease

Entry Detail

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General Information

Database ID: exR0764410 RNA Name: TAGLN2 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 159918107 End Site(bp): 159925732 External Links: ENSG00000158710

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004922.1 chr7 99325879 99394653 + AC010422.3 chr19 12643831 12648397 - AC011462.1 chr19 41350853 41425001 + AC090360.1 chr18 80034346 80097088 + AC093525.2 chr16 2496032 2520218 + ACADVL chr17 7217125 7225266 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR8 chr3 53867066 53882152 - ADD3 chr10 109996368 110135565 + ADIPOR2 chr12 1688574 1788674 + ADPRHL2 chr1 36088892 36093932 + ADRM1 chr20 62302093 62308862 + AGK chr7 141551278 141655244 + AK4 chr1 65147549 65232145 + AKIP1 chr11 8911139 8920084 + AL035078.4 chr11 31812391 32104665 + AL136454.1 chr1 192716132 192716653 + AL590764.2 chrX 71103987 71111575 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-652-3p chrX 110055389 110055409 + hsa-miR-1294 chr5 154347153 154347174 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC067852.2 chr17 42552436 42554748 - AC132192.2 chr11 9459556 9460702 - AL008721.2 chr22 25476218 25479971 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.