exRNAdisease

Entry Detail

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General Information

Database ID: exR0764426 RNA Name: TARDBP RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 11012344 End Site(bp): 11026420 External Links: ENSG00000120948

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011448.1 chr19 19516227 19536076 + AC015813.2 chr17 57989038 58007246 - AC073508.2 chr17 40627356 40665141 - AC091167.2 chr15 90249556 90272208 + AC120057.2 chr17 7240427 7244635 - ACLY chr17 41866917 41930542 - ACOT2 chr14 73567620 73575658 + ACTA1 chr1 229431245 229434098 - ACTG1 chr17 81509971 81523847 - ADD1 chr4 2843857 2930076 + AGTRAP chr1 11736084 11754802 + AL136454.1 chr1 192716132 192716653 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-130a-3p chr11 57641252 57641273 + hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-454-3p chr17 59137787 59137809 - hsa-miR-302e chr11 7234771 7234787 + hsa-let-7d-3p chr9 94178895 94178916 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012485.1 chr2 238231684 238255633 + AC016876.2 chr17 7581964 7584086 - AC079781.5 chr7 97851688 97972985 - AC092490.1 chr12 8788253 8795789 + AC106864.1 chr4 112693047 112706810 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.