exRNAdisease

Entry Detail

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General Information

Database ID: exR0764883 RNA Name: TNPO2 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 12699194 End Site(bp): 12724011 External Links: ENSG00000105576

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAMP chr2 218264123 218270257 - ABCE1 chr4 145098288 145129524 + ABL2 chr1 179099330 179229684 - AC007040.2 chr2 70939318 70995336 - AC010422.3 chr19 12643831 12648397 - AC011462.1 chr19 41350853 41425001 + AC011530.1 chr19 45779437 45785973 - AC091167.2 chr15 90249556 90272208 + AC092647.5 chr7 55887277 55955239 + ACACA chr17 37084992 37406836 - ACADVL chr17 7217125 7225266 + ACTB chr7 5527148 5563784 - ADAM11 chr17 44758988 44781846 + ADAM8 chr10 133262420 133276868 - ADARB1 chr21 45073853 45226560 + ADCK2 chr7 140672945 140696261 + ADGRE5 chr19 14380501 14408725 + ADGRG2 chrX 18989307 19122637 - AGAP1 chr2 235494043 236131800 + AGAP3 chr7 151085831 151144436 + AGPAT5 chr8 6708642 6761503 + AGRN chr1 1020120 1056118 + AL136295.4 chr14 24180395 24190416 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4787-5p chr3 50675093 50675114 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006538.1 chr19 2727743 2729327 - AC011753.2 chr2 109594693 109605698 - AC084125.2 chr8 144495458 144505444 - AC109460.3 chr16 28974804 28990775 + AD000090.1 chr19 35557956 35581954 + AGAP11 chr10 86970741 87010126 + AL049796.1 chr1 93847174 93848939 + AL117379.1 chr20 62928621 62929297 - AL136982.1 chr10 86992406 87010203 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.