exRNAdisease

Entry Detail

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General Information

Database ID: exR0764958 RNA Name: TPT1 RNA Type: mRNA Chromosome: chr13 Starnd: - Coordinate: Start Site(bp): 45333471 End Site(bp): 45341370 External Links: ENSG00000133112

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCB4 chr7 87401697 87480435 - AK2 chr1 33007940 33080996 - AKAP17A chrX 1591604 1602520 + AARSD1 chr17 42950526 42964498 - AGBL2 chr11 47659591 47715389 - AC092718.8 chr16 81022316 81096284 - AKAP1 chr17 57085092 57121346 + ADM chr11 10305073 10307397 + AL136454.1 chr1 192716132 192716653 + AAGAB chr15 67200667 67255195 - ACAP1 chr17 7336529 7351477 + AC105052.1 chr7 102582523 102642869 - AC112229.3 chr2 110402934 110473075 - AL121594.1 chr14 35122549 35317474 + ABR chr17 1003518 1229738 - AC005258.1 chr19 2269525 2341172 + AIFM2 chr10 70098223 70132934 - ADK chr10 74151202 74709963 + AL121753.1 chr20 35267885 35280043 - ACIN1 chr14 23058564 23095614 - AC073082.1 chr2 48632291 48755724 - AGO4 chr1 35808016 35857890 + AC073508.2 chr17 40627356 40665141 - AC120057.2 chr17 7240427 7244635 - AC010323.1 chr19 8308283 8321379 - ACBD3 chr1 226144679 226186741 - ADAR chr1 154582057 154628013 - ACTR1B chr2 97655939 97664044 - ACAD8 chr11 134253495 134265855 + ADD3 chr10 109996368 110135565 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3648 chr21 8987026 8987046 + hsa-miR-4426 chr1 192716333 192716349 + hsa-miR-4700-5p chr12 120723202 120723223 + hsa-miR-4700-3p chr12 120723233 120723258 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005062.1 chr7 19918981 20140453 - AC007952.4 chr17 19112000 19112636 - AC012321.1 chr16 69703065 69704652 + AC012531.2 chr12 54017110 54035361 + AC016876.2 chr17 7581964 7584086 - AC019155.2 chr7 125229579 125264291 - AC020663.1 chr16 4730115 4752565 - AC026362.1 chr12 122975320 122982907 + AC064802.1 chr8 114282067 114295839 + AC079781.5 chr7 97851688 97972985 - AC091564.7 chr11 6610883 6616594 - AC113414.1 chr5 162424042 163437326 - AC132217.1 chr11 2129121 2129964 - AC242426.2 chr1 147172755 147295734 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL096870.2 chr14 24209646 24215987 - AL121749.1 chr10 35604485 35608153 - AL136295.6 chr14 24198433 24199090 + AL137058.2 chr13 52600042 52642542 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.