exRNAdisease

Entry Detail

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General Information

Database ID: exR0765165 RNA Name: TUBA1A RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 49184795 End Site(bp): 49189080 External Links: ENSG00000167552

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC124312.1 chr15 24955034 25000276 + ACSS2 chr20 34872146 34927962 + ADA2 chr22 17178790 17258235 - AC120057.2 chr17 7240427 7244635 - AHCY chr20 34280268 34311802 - AC093525.2 chr16 2496032 2520218 + ADORA2A chr22 24417879 24442357 + AC005832.4 chr12 4604944 4662643 + AC048338.1 chr12 122207779 122266423 - AIF1 chr6 31615217 31617021 + ABHD4 chr14 22598237 22613215 + ALDH3A2 chr17 19648136 19685760 + ACTB chr7 5527148 5563784 - AFDN chr6 167826922 167972023 + AC092073.1 chr19 34396315 34409364 + AC092143.1 chr16 89919165 89936092 + ALDOA chr16 30064164 30070457 + AAR2 chr20 36236459 36270918 + ACTR2 chr2 65227753 65271253 + ABCF1 chr6 30571393 30597179 + AC245033.1 chr15 82536788 82573194 - AC010422.3 chr19 12643831 12648397 - ADM chr11 10305073 10307397 + ACBD5 chr10 27195214 27242130 - ABCA7 chr19 1039997 1065572 + AKAP17A chrX 1591604 1602520 + ACTR3 chr2 113890063 113962596 + ACTG1 chr17 81509971 81523847 - AGRN chr1 1020120 1056118 + AC005943.1 chr19 1578339 1605445 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-367-3p chr4 112647877 112647898 - hsa-miR-198 chr3 120395703 120395724 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002116.1 chr19 36008638 36014235 - AC016876.2 chr17 7581964 7584086 - AC020928.1 chr19 36773112 36777078 + AC023509.1 chr12 53441741 53467528 + AC026362.1 chr12 122975320 122982907 + AC106864.1 chr4 112693047 112706810 - AC132217.1 chr11 2129121 2129964 - AC133644.3 chr2 87455476 87767359 + AD000090.1 chr19 35557956 35581954 + AF106564.1 chr8 24912165 24914717 - AL021707.2 chr22 38667585 38681847 - AL049795.2 chr1 32170733 32176568 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.