exRNAdisease

General Information

Database ID:

exR0765166

RNA Name:

TUBA1B

RNA Type:

mRNA

Chromosome:

chr12

Starnd:

Coordinate:

Start Site(bp):

49127782

End Site(bp):

49131397

External Links:

Disease Information

Disease Name:	Glioblastoma Multiforme
Disease Category:	Cancers
MeSH ID:	D005909
Type:	Neoplasms/Neoplasms, Glandular and Epithelial
Alias:	Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID:	GSE106804
Description:	Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:	Cancer vs Control
Case Disease Type:	Glioblastoma Multiforme
Case Disease SubType:	NA
Case Sample:	Glioblastoma Multiforme
Control Sample:	Healthy
Number of Case:	13
Number of Control:	6
Number of Samples:	19

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ADIPOR1	chr1	202940826	202958572	-
AKIRIN1	chr1	38991276	39006059	+
AEN	chr15	88621337	88632281	+
ADCY5	chr3	123282296	123449758	-
ALDOA	chr16	30064164	30070457	+
AK2	chr1	33007940	33080996	-
ADRM1	chr20	62302093	62308862	+
ABRACL	chr6	139028745	139043302	+
ACSS2	chr20	34872146	34927962	+
AGFG2	chr7	100539203	100568220	+
ACTN4	chr19	38647649	38731589	+
AGBL5	chr2	27042364	27070622	+
ABI2	chr2	203328239	203447728	+
AC008878.3	chr19	7382834	7470241	+
ADGRG6	chr6	142301854	142446266	+
ACVR2B	chr3	38453890	38493142	+
AC120057.2	chr17	7240427	7244635	-
AC138811.2	chr16	18788063	18801519	-
ABHD14A-ACY1	chr3	51974706	51989183	+
ADD1	chr4	2843857	2930076	+
AC004922.1	chr7	99325879	99394653	+
ADSL	chr22	40346500	40390463	+
ACTG1	chr17	81509971	81523847	-
ADA	chr20	44619522	44652233	-
AC007192.1	chr19	18153158	18178117	+
AC007040.2	chr2	70939318	70995336	-
AC015813.2	chr17	57989038	58007246	-
ADAR	chr1	154582057	154628013	-
AC011448.1	chr19	19516227	19536076	+
AL136454.1	chr1	192716132	192716653	+

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-103a-3p	chr5	168560904	168560926	-
hsa-miR-106a-5p	chrX	134170244	134170266	-
hsa-miR-221-3p	chrX	45746180	45746202	-
hsa-miR-302c-3p	chr4	112648366	112648388	-
hsa-miR-652-3p	chrX	110055389	110055409	+
hsa-miR-1291	chr12	48654494	48654517	-
hsa-miR-3654	chr7	133034860	133034878	-
hsa-miR-4707-5p	chr14	22956998	22957020	-

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC005618.1	chr5	141326210	141329357	+
AC007952.4	chr17	19112000	19112636	-
AC012485.1	chr2	238231684	238255633	+
AC016876.2	chr17	7581964	7584086	-
AC022167.2	chr16	8848105	8860456	+
AC023509.1	chr12	53441741	53467528	+
AC026362.1	chr12	122975320	122982907	+
AC069281.2	chr7	100572232	100578700	-
AC087190.3	chr16	9104848	9113181	+
AC104461.1	chr1	200333193	200478669	+
AC124067.3	chr8	37559992	37567477	+
AC245014.3	chr1	145281116	145281462	+
AD000090.1	chr19	35557956	35581954	+
AL049543.1	chr6	28587378	28591747	+
AL118516.1	chr22	46761894	46762563	-

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	29330365
Title:	Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:	Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:	Nat Commun. 2018 Jan 12;9(1):175.
Description:	Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.