exRNAdisease

Entry Detail

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General Information

Database ID: exR0765170 RNA Name: TUBB RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 30720352 End Site(bp): 30725426 External Links: ENSG00000196230

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AIF1L chr9 131096476 131123152 + AHI1 chr6 135283532 135497765 - AC091959.3 chr5 146203550 146339251 + ADGRL2 chr1 81306160 81992436 + AL022238.4 chr22 40346529 40410054 + ACADS chr12 120725774 120740008 + AC015813.2 chr17 57989038 58007246 - AATF chr17 36948954 37056871 + AACS chr12 125065434 125143333 + AKR1A1 chr1 45550543 45570049 + AC025165.3 chr12 57772660 57797554 + ADGRV1 chr5 90529344 91164437 + AGO1 chr1 35869808 35930532 + ABHD10 chr3 111979010 111993368 + AC010132.3 chr7 42909273 42932174 - ACAP1 chr17 7336529 7351477 + AC048338.1 chr12 122207779 122266423 - AC006030.1 chr2 74211604 74363377 - ADH5 chr4 99070978 99088801 - ACBD6 chr1 180269653 180502954 - AAMP chr2 218264123 218270257 - AIG1 chr6 143060496 143341058 + ACTB chr7 5527148 5563784 - AC013394.1 chr15 92883413 92949230 + AL590132.1 chr1 210858125 211134146 - AHSA1 chr14 77457870 77469472 + ALDH18A1 chr10 95605941 95656711 - AKAP8 chr19 15353385 15379798 - ACTG1 chr17 81509971 81523847 - ACTR3 chr2 113890063 113962596 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-92a-3p chrX 134169544 134169565 - hsa-miR-3198 chr12 54231407 54231428 - hsa-miR-3654 chr7 133034860 133034878 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC004687.1 chr17 58330884 58332508 - AC010729.1 chr2 5726253 5730355 + AC012360.3 chr2 105334027 105337475 - AC016876.2 chr17 7581964 7584086 - AC019205.1 chr6 73263212 73301789 + AC022167.2 chr16 8848105 8860456 + AC023509.1 chr12 53441741 53467528 + AC026362.1 chr12 122975320 122982907 + AC068134.1 chr2 232379635 232381674 - AC092171.3 chr7 5426277 5428927 - AC099522.2 chr5 73497550 73498293 - AC114271.1 chr19 10333436 10336248 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL023653.1 chrX 129794994 129796963 + AL049543.1 chr6 28587378 28591747 + AL132780.1 chr14 22929607 22956374 + AL133215.2 chr10 101060029 101061005 - AL137058.2 chr13 52600042 52642542 + AL137127.1 chr1 19072110 19075511 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.