exRNAdisease

Entry Detail

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General Information

Database ID: exR0765173 RNA Name: TUBB4B RNA Type: mRNA Chromosome: chr9 Starnd: + Coordinate: Start Site(bp): 137241287 End Site(bp): 137243707 External Links: ENSG00000188229

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD5 chr3 43690108 43734371 + ABLIM1 chr10 114431113 114768061 - AC004922.1 chr7 99325879 99394653 + AC008764.1 chr19 16479067 16628204 - AC011511.4 chr19 10315471 10320678 - AC068533.4 chr7 66087761 66152277 + AC092143.1 chr16 89919165 89936092 + ACBD6 chr1 180269653 180502954 - ACLY chr17 41866917 41930542 - ACSS2 chr20 34872146 34927962 + ACTR2 chr2 65227753 65271253 + ADAM10 chr15 58588809 58749791 - AEBP2 chr12 19404045 19720801 + AEN chr15 88621337 88632281 + AGO4 chr1 35808016 35857890 + AGRN chr1 1020120 1056118 + AIMP2 chr7 6009255 6023834 + AKAP7 chr6 131135467 131283535 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008105.3 chr17 45190931 45222222 - AC008738.5 chr19 33301279 33301940 + AC016355.1 chr15 67541072 67542604 - AC022075.1 chr12 10363638 10398506 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.