exRNAdisease

Entry Detail

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General Information

Database ID: exR0765228 RNA Name: UBA52 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 18571730 End Site(bp): 18577550 External Links: ENSG00000221983

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + ABRACL chr6 139028745 139043302 + AC008763.3 chr19 7678501 7682854 + AC008982.1 chr19 38817471 38840178 - AC010422.3 chr19 12643831 12648397 - AC012254.2 chr18 47108188 47176345 - AC023055.1 chr12 55757275 55827546 - AC124312.1 chr15 24955034 25000276 + AC245033.1 chr15 82536788 82573194 - ACAT2 chr6 159762045 159779112 + ACLY chr17 41866917 41930542 - ACO1 chr9 32384603 32454769 + ACSF3 chr16 89088375 89164121 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR2 chr2 65227753 65271253 + AD000671.1 chr19 35745678 35754519 + ADAR chr1 154582057 154628013 - ADPGK chr15 72751369 72785846 - ADRM1 chr20 62302093 62308862 + AFF4 chr5 132875395 132963634 - AHCY chr20 34280268 34311802 - AIF1L chr9 131096476 131123152 + AIP chr11 67483026 67491103 + AL121594.1 chr14 35122549 35317474 + AL136295.5 chr14 24147548 24166452 + AL136454.1 chr1 192716132 192716653 + AL512428.1 chr6 24797373 24809798 - AL590764.2 chrX 71103987 71111575 - AL645941.2 chr6 32937364 32953122 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC021078.1 chr5 149494314 149504670 - AC099329.1 chr3 42785087 42852428 - AC109460.3 chr16 28974804 28990775 + AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + AL021368.4 chr6 57919912 57961382 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.