exRNAdisease

Entry Detail

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General Information

Database ID: exR0765241 RNA Name: UBC RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 124911604 End Site(bp): 124917368 External Links: ENSG00000150991

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF2 chr7 151207837 151227166 - AC008982.1 chr19 38817471 38840178 - AC018523.2 chr11 14493783 14520344 - AC026954.2 chr17 7312661 7319174 - AC118553.2 chr1 99970011 100083321 + AC124312.1 chr15 24955034 25000276 + AC138811.2 chr16 18788063 18801519 - ACADVL chr17 7217125 7225266 + ACOT2 chr14 73567620 73575658 + ACP5 chr19 11574660 11579008 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACY1 chr3 51983340 51989197 + ADAM10 chr15 58588809 58749791 - ADIPOR2 chr12 1688574 1788674 + AEN chr15 88621337 88632281 + AFF1 chr4 86935002 87141054 + AFP chr4 73431138 73456174 + AGPAT1 chr6 32168212 32178096 - AKIRIN2 chr6 87674860 87702233 - AL133352.1 chr10 100505628 100529881 - AL136295.1 chr14 24189157 24213473 - AL136295.4 chr14 24180395 24190416 - AL136454.1 chr1 192716132 192716653 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-492 chr12 94834427 94834449 + hsa-miR-1244 chr2 231713368 231713393 + hsa-miR-4426 chr1 192716333 192716349 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC048341.1 chr12 62602752 62622213 + AC069281.2 chr7 100572232 100578700 - AC091564.7 chr11 6610883 6616594 - AC139149.1 chr17 81514047 81527776 + AL022311.1 chr22 37876148 37895563 + AL117378.1 chr6 131901963 131920565 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.