exRNAdisease

Entry Detail

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General Information

Database ID: exR0765247 RNA Name: UBE2D3 RNA Type: mRNA Chromosome: chr4 Starnd: - Coordinate: Start Site(bp): 102794383 End Site(bp): 102868896 External Links: ENSG00000109332

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + ABCB7 chrX 75051048 75156732 - AC010422.3 chr19 12643831 12648397 - AC017083.3 chr2 68131238 68261230 - AC022384.1 chr3 10249372 10285796 + AC084337.2 chr11 6481485 6508978 + AC092143.1 chr16 89919165 89936092 + ACACA chr17 37084992 37406836 - ACSL3 chr2 222860942 222944639 + ACTB chr7 5527148 5563784 - ACTR3 chr2 113890063 113962596 + ACTR6 chr12 100199122 100241865 + ACYP1 chr14 75053237 75069483 - ADD3 chr10 109996368 110135565 + ADGRV1 chr5 90529344 91164437 + AGL chr1 99850361 99924023 + AHCYL1 chr1 109984765 110023742 + AHSA1 chr14 77457870 77469472 + AIF1L chr9 131096476 131123152 + AK4 chr1 65147549 65232145 + AKIRIN2 chr6 87674860 87702233 - AKR1A1 chr1 45550543 45570049 + ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009133.5 chr16 29808679 29812227 + AC020663.1 chr16 4730115 4752565 - AL117378.1 chr6 131901963 131920565 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.