exRNAdisease

Entry Detail

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General Information

Database ID: exR0765384 RNA Name: USP22 RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 20999596 End Site(bp): 21043760 External Links: ENSG00000124422

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AARS2 chr6 44298731 44313347 - ABCB1 chr7 87503017 87713323 - AC005726.1 chr17 28455752 28614185 - AC008581.2 chr5 77030902 77152155 + AC008695.1 chr5 131425891 131796983 - AC010422.3 chr19 12643831 12648397 - AC138811.2 chr16 18788063 18801519 - ACBD3 chr1 226144679 226186741 - ACIN1 chr14 23058564 23095614 - ACLY chr17 41866917 41930542 - ADH5 chr4 99070978 99088801 - ADSL chr22 40346500 40390463 + AGGF1 chr5 77029251 77065234 + AHCY chr20 34280268 34311802 - AKR1B1 chr7 134442356 134459284 - AL022238.4 chr22 40346529 40410054 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-148b-3p chr12 54337278 54337299 + hsa-miR-485-5p chr14 101055427 101055448 + hsa-miR-650 chr22 22822791 22822811 + hsa-miR-371a-5p chr19 53787680 53787699 + hsa-miR-616-3p chr12 57519183 57519204 - hsa-miR-665 chr14 100875075 100875094 + hsa-miR-1321 chrX 85835832 85835849 + hsa-miR-4508 chr15 23562107 23562123 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006064.5 chr12 6510275 6510522 + AC007952.4 chr17 19112000 19112636 - AC011445.1 chr19 39314651 39320858 - AC016876.2 chr17 7581964 7584086 - AC026362.1 chr12 122975320 122982907 + AC067852.1 chr17 42536510 42562062 + AC067930.1 chr8 143579636 143580670 + AC087190.3 chr16 9104848 9113181 + AC111170.2 chr17 77469162 77472770 - AC133644.3 chr2 87455476 87767359 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.