exRNAdisease

Entry Detail

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General Information

Database ID: exR0765450 RNA Name: VCP RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 35056064 End Site(bp): 35072627 External Links: ENSG00000165280

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AACS chr12 125065434 125143333 + ABHD12 chr20 25294742 25390835 - AC005258.1 chr19 2269525 2341172 + AC010422.3 chr19 12643831 12648397 - AC073896.1 chr12 56285916 56316059 - AC091167.2 chr15 90249556 90272208 + AC093525.2 chr16 2496032 2520218 + ACADS chr12 120725774 120740008 + ACBD6 chr1 180269653 180502954 - ACTG1 chr17 81509971 81523847 - ADAR chr1 154582057 154628013 - ADH5 chr4 99070978 99088801 - AL121753.1 chr20 35267885 35280043 - ALDH2 chr12 111766887 111817532 + ALDH7A1 chr5 126531200 126595362 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-331-3p chr12 95308480 95308500 + hsa-miR-339-5p chr7 1022990 1023012 - hsa-miR-520a-5p chr19 53690895 53690915 + hsa-miR-450b-5p chrX 134540231 134540252 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002310.1 chr16 30534752 30537149 + AC112484.1 chr3 128860620 128871540 - AC132217.1 chr11 2129121 2129964 - AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL031282.2 chr1 1702736 1737688 - AL121992.1 chr1 15586136 15603626 - AL135925.1 chr10 79825902 79827602 + AL136985.3 chr1 58715609 58771295 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.