exRNAdisease

Entry Detail

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General Information

Database ID: exR0765580 RNA Name: WDR74 RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 62832342 End Site(bp): 62841809 External Links: ENSG00000133316

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AARS2 chr6 44298731 44313347 - ABCA13 chr7 48171458 48647497 + ABL2 chr1 179099330 179229684 - AC005943.1 chr19 1578339 1605445 - AC006064.6 chr12 6556886 6607367 - AC011005.1 chr7 129126518 129130793 + AC011448.1 chr19 19516227 19536076 + AC126283.2 chr4 109713916 109801999 - AC245033.1 chr15 82536788 82573194 - ACO2 chr22 41469117 41528989 + ACTG1 chr17 81509971 81523847 - ADARB1 chr21 45073853 45226560 + AHSA1 chr14 77457870 77469472 + AKAP12 chr6 151239967 151358559 + AKR1A1 chr1 45550543 45570049 + AL136295.4 chr14 24180395 24190416 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-1246 chr2 176601024 176601042 - hsa-miR-3609 chr7 98881700 98881723 + hsa-miR-664b-5p chrX 154768596 154768619 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006064.5 chr12 6510275 6510522 + AC007952.4 chr17 19112000 19112636 - AC010442.1 chr5 466124 473098 - AC114781.2 chr4 83233512 83247213 - AC245014.3 chr1 145281116 145281462 + AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.