exRNAdisease

Entry Detail

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General Information

Database ID: exR0765651 RNA Name: XRCC5 RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 216107464 End Site(bp): 216206303 External Links: ENSG00000079246

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + AC002985.1 chr19 18907013 18934397 - AC023055.1 chr12 55757275 55827546 - AC097637.1 chr3 52221081 52231190 - AC107871.1 chr15 68184032 68229718 - AC120057.2 chr17 7240427 7244635 - AC124312.1 chr15 24955034 25000276 + AC244197.3 chrX 149477104 149540926 - AC245033.1 chr15 82536788 82573194 - ACO1 chr9 32384603 32454769 + ACSS2 chr20 34872146 34927962 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR2 chr2 65227753 65271253 + ADA chr20 44619522 44652233 - ADGRA3 chr4 22345071 22516066 - ADIPOR2 chr12 1688574 1788674 + AFF1 chr4 86935002 87141054 + AHCY chr20 34280268 34311802 - AIF1L chr9 131096476 131123152 + AIMP1 chr4 106315544 106349456 + AKIRIN1 chr1 38991276 39006059 + AKR1A1 chr1 45550543 45570049 + AL136295.4 chr14 24180395 24190416 - AL162417.1 chr9 133098121 133163914 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC040162.3 chr16 67882461 67886367 + AC136475.2 chr11 310139 311141 - AC245033.4 chr15 82533175 82540008 - AFDN-DT chr6 167822103 167826812 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.