exRNAdisease

Entry Detail

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General Information

Database ID: exR0765662 RNA Name: YBX1 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 42682418 End Site(bp): 42703805 External Links: ENSG00000065978

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABL1 chr9 130713016 130887675 + ABR chr17 1003518 1229738 - AC008764.4 chr19 16577642 16660115 - AC010422.3 chr19 12643831 12648397 - AC092143.1 chr16 89919165 89936092 + AC118553.2 chr1 99970011 100083321 + AC120057.2 chr17 7240427 7244635 - AC138811.2 chr16 18788063 18801519 - ACAD8 chr11 134253495 134265855 + ACKR3 chr2 236567787 236582354 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADAM11 chr17 44758988 44781846 + ADD2 chr2 70607618 70768225 - ADGRL2 chr1 81306160 81992436 + AEBP2 chr12 19404045 19720801 + AEN chr15 88621337 88632281 + AFG3L2 chr18 12328944 12377227 - AGL chr1 99850361 99924023 + AGO3 chr1 35930718 36072500 + AGO4 chr1 35808016 35857890 + AKR1E2 chr10 4786629 4848062 + AKT1 chr14 104769349 104795751 - AL136454.1 chr1 192716132 192716653 + AL928654.3 chr14 105487199 105492267 + ALDH9A1 chr1 165662216 165698863 - ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC018521.1 chr17 47945424 47981736 + AC245014.3 chr1 145281116 145281462 + AL031320.2 chr6 143484979 143507327 + AL121992.1 chr1 15586136 15603626 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.