exRNAdisease

Entry Detail

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General Information

Database ID: exR0765690 RNA Name: YWHAQ RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 9583967 End Site(bp): 9630997 External Links: ENSG00000134308

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAGAB chr15 67200667 67255195 - ABCA2 chr9 137007234 137028922 - ABCB7 chrX 75051048 75156732 - ABCC4 chr13 95019835 95301475 - ABI2 chr2 203328239 203447728 + ABRACL chr6 139028745 139043302 + AC010323.1 chr19 8308283 8321379 - AC011005.1 chr7 129126518 129130793 + AC018523.2 chr11 14493783 14520344 - AC245033.1 chr15 82536788 82573194 - ACADSB chr10 123008979 123058290 + ACAP1 chr17 7336529 7351477 + ACTN4 chr19 38647649 38731589 + ADAT2 chr6 143422832 143450695 - ADO chr10 62804720 62808479 + AFTPH chr2 64524305 64593005 + AKAP13 chr15 85380571 85749358 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-5047 chr17 64501230 64501250 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC023509.1 chr12 53441741 53467528 + AC079781.5 chr7 97851688 97972985 - AC126365.1 chr17 20788071 20789584 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.