exRNAdisease

Entry Detail

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General Information

Database ID: exR0765937 RNA Name: ZNF354B RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 178859953 End Site(bp): 178888122 External Links: ENSG00000178338

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008982.1 chr19 38817471 38840178 - AC009690.3 chr15 72266746 72319946 - AC093668.1 chr7 102541501 102592444 - ACAD9 chr3 128879596 128916067 + ACLY chr17 41866917 41930542 - ACSF3 chr16 89088375 89164121 + ACTB chr7 5527148 5563784 - ACTR1A chr10 102461881 102502712 - ADAM15 chr1 155050566 155062775 + ADAM19 chr5 157395534 157575775 - ADARB1 chr21 45073853 45226560 + ADD2 chr2 70607618 70768225 - ADSL chr22 40346500 40390463 + AHCY chr20 34280268 34311802 - AHCYL1 chr1 109984765 110023742 + AIF1L chr9 131096476 131123152 + AKAP13 chr15 85380571 85749358 + AKT2 chr19 40230317 40285536 - AL021546.1 chr12 120438198 120460006 + AL022238.4 chr22 40346529 40410054 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4517 chr16 28958587 28958611 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC005899.4 chr17 32328441 32329395 + AC007952.4 chr17 19112000 19112636 - AC011445.1 chr19 39314651 39320858 - AC067930.1 chr8 143579636 143580670 + AC084082.1 chr8 66112667 66126632 + AC144548.1 chr12 110387463 110445548 - AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL117378.1 chr6 131901963 131920565 + AL132780.1 chr14 22929607 22956374 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.