Help

 

1. Cancer Type Abbreviation

AbbreviationCancer typeAbbreviationCancer type
ADCAAdrenocortical CancerBTCABiliary Tract Cancer
BLCABladder CancerBNCABrain Cancer
BRCABreast CancerCECACervical Cancer
CHORChordomaCOADColon Cancer
CLCAColorectal CancerENCAEndometrial Cancer
ESCAEsophageal CancerGSCAGastric Cancer
GASTGastrointestinal Stromal TumorHNSCHead and Neck Cancer
LIHCHepatocellular CarcinomaKDCAKidney Cancer
LEUKLeukemiaLICALiver Cancer
LUCALung CancerLYMPLymphoma
MELAMelanomaMESOMesothelioma
NSCANeuroendocrine NeoplasiaNDCANeuroendocrine Neoplasia
OSCAOral Squamous Cell CarcinomaOVCAOvarian Cancer
PNCAPancreatic CancerPRCAProstate Cancer
RETIRetinoblastomaSCRASarcoma
SKCASkin CancerSINTSmall Intestinal Neuroendocrine Tumor
TECATesticular CancerTHCAThyroid Cancer
TOCATonsil CancerUTCAUterus Cancer

 

2. Data Source
All the miRNA expression data sets were collected from publicly available resources. The table below lists data sets collected from GEO database, the GEO series, Cancer Type, GEO platform ID, Pubmed ID, and the total number of samples for each dataset were listed. In addition, data sets collected from TCGA are also included.

GEO seriesCancer typeGEO platformPubmed IDNumber of Samples
GSE2399lymphoma, leukemiaGPL18991594470740
GSE2564breast cancer, renal carcinoma, lung cancer, prostate cancer, uterus carcinomaGPL198615944708334
GSE4589breast cancerGPL32381678453820
GSE5244uterus cancerGPL38791724316351
GSE6188esophageal cancerGPL450818172293257
GSE6636prostate cancerGPL3238 -47
GSE7072retinoblastomaGPL4879180261116
GSE7842breast cancerGPL517317922911119
GSE8126prostate cancerGPL5180 1867683976
GSE10259colorectal cancerGPL44111984333666
GSE10694hepatocellular carcinomaGPL6542 18649363166
GSE11016kidney cancerGPL66681851966032
GSE11163head and neck cancerGPL6690 1935174727
GSE12105kidney cancerGPL69551922826224
GSE12303brain cancerGPL7114 1897322848
GSE12933lymphomasGPL7373190476788
GSE13030brain cancerGPL7389 -93
GSE14857prostate cancerGPL69551967604524
GSE15008lung cancerGPL8176-375
GSE16025lung cancerGPL51061958427371
GSE16456esophageal cancerGPL69551973794932
GSE16558lymphomaGPL8695 -65
GSE17792brain cancerGPL74361970399317
GSE20099esophageal cancerGPL88712112827951
GSE6857hepatocellular carcinomaGPL470018176954482
GSE7055prostate cancerGPL470018459106114
GSE7828colon cancerGPL470018230780170
GSE15885breast cancerGPL61271943296129
GSE17498lymphomaGPL822719846888102
GSE18509melanomaGPL90812030495416
GSE18392colon cancerGPL817819922656145
GSE19856adrenocortical tumorGPL82272048403630
GSE19387melanomaGPL90812035781740
GSE22058hepatocellular carcinomaGPL10457 20739924397
GSE21036prostate cancerGPL8227 20579941142
GSE23022prostate cancerGPL87862140051440
GSE24390brain cancerGPL74362115664824
GSE24485lymphomaGPL82272146024222
GSE18546sarcomaGPL7738 -20
GSE24996melanomaGPL69552189302031
GSE19783breast cancerGPL822721364938216
GSE20077hepatocellular carcinomaGPL82272205688111
GSE19980hepatocellular carcinomaGPL9954 -12
GSE21362hepatocellular carcinomaGPL1031221298008146
GSE28700gastric cancerGPL90812170300644
GSE29352pancreatic cancerGPL13606-43
GSE26245prostate cancerGPL11350-96
GSE22816adrenocortical tumorGPL133472185992752
GSE22216breast cancerGPL817821737487210
GSE22420lymphomaGPL1055421701491150
GSE24508breast cancerGPL10349 2137573319
GSE23383ovarian cancerGPL9735218116256
GSE23739gastric cancerGPL77312141521280
GSE32232lymphomaGPL90812211025146
GSE25820pancreatic cancerGPL77312195329318
GSE32678pancreatic cancerGPL77232226181032
GSE25653melanomaGPL69552143519356
GSE31741gastrointestinal stromal tumorGPL104062225845332
GSE30454colorectal cancerGPL81792184400974
GSE31377lymphomaGPL82272192104156
GSE33961colorectal cancerGPL7731-12
GSE26323hepatocellular carcinomaGPL11362234781896
GSE35579melanomaGPL15183-71
GSE31629leukemiaGPL77312226479362
GSE32906nasopharyngeal carcinomaGPL11350 -22
GSE35412breast cancerGPL97312243887175
GSE35602colorectal cancerGPL82272245293959
GSE29965esophageal cancerGPL77222250466512
GSE31045sarcomaGPL7723 2235041425
GSE29135lung cancerGPL817922331473387
GSE29491lymphomaGPL8617 2147842926
GSE28955pancreatic cancerGPL6955-23
GSE37407breast cancerGPL137032229448861
GSE28090lymphomaGPL114872210271025
GSE36682nasopharyngeal carcinomaGPL15311-68
GSE35794endometrial cancerGPL10850-22
GSE30656cervical cancerGPL69552233014147
GSE32960nasopharyngeal carcinomaGPL1472223408429330
GSE25631brain cancerGPL8179 2257042687
GSE33743gastric cancerGPL148952245078141
GSE36681lung cancerGPL817922573352206
GSE28100oral squamous cell carcinoma GPL108502276142720
GSE29248lung cancerGPL81792204629612
GSE32957liver cancerGPL147322270740835
GSE37527breast cancerGPL147672296402312
GSE39678hepatocellular carcinomaGPL158522349989424
GSE38389colorectal cancerGPL1103922850566140
GSE41282kidney cancerGPL87862379984938
GSE28423sarcomaGPL82272313355223
GSE40525breast cancerGPL822723125021120
GSE34460melanomaGPL150192311177321
GSE38781pancreatic cancerGPL14903 2315545719
GSE33125colon cancerGPL81792302878718
GSE33332kidney cancerGPL108502323966512
GSE39486brain cancerGPL15829229213986
GSE33232head and neck cancerGPL8786-284
GSE35982colorectal cancerGPL147672270358632
GSE19945lung cancerGPL9948-63
GSE36802prostate cancerGPL87862323373642
GSE40744hepatocellular carcinomaGPL146132339000076
GSE33568small intestinal neuroendocrine tumorGPL8786 2332897725
GSE45264lymphomaGPL16770-22
GSE45604prostate cancerGPL146132451878560
GSE36915hepatocellular carcinomaGPL81792261300589
GSE31164hepatocellular carcinomaGPL1085023496901110
GSE37053lymphomaGPL82272361331857
GSE47764liver cancerGPL11487241693436
GSE29742neuroendocrine neoplasiaGPL82272366087254
GSE26595gastric cancerGPL8179 2422295168
GSE40355bladder cancerGPL8227-48
GSE47582kidney cancerGPL87862418914626
GSE40345mesotheliomaGPL81792382822931
GSE41874hepatocellular carcinomaGPL7722-10
GSE45666breast cancerGPL1476723722663116
GSE49246colon cancerGPL17496 2423920880
GSE32922breast cancerGPL7723-38
GSE41369pancreatic cancerGPL161422412047618
GSE43796pancreatic cancerGPL151592407218131
GSE29622colon cancerGPL11162 2236206965
GSE35834colon cancerGPL878623987127158
GSE42906lymphomaGPL90812412116455
GSE44124breast cancerGPL147672409845253
GSE47841ovarian cancerGPL146132451262030
GSE50505kidney cancerGPL176672429805428
GSE51908leukemiaGPL8786 25368993190
GSE54088colorectal cancerGPL8178 2606925134
GSE54397gastric cancerGPL151592516780132
GSE54492melanomaGPL102622565066225
GSE31277head and neck cancerGPL97702420963842
GSE38167breast cancerGPL149432447944667
GSE40807thyroid cancerGPL82272703603080
GSE41012colorectal cancerGPL7724 -35
GSE41032brain cancerGPL15516245196636
GSE41655colorectal cancerGPL11487-107
GSE43039nasopharyngeal carcinomaGPL16414 2460663340
GSE44899breast cancerGPL7723 2491746380
GSE45238oral squamous cell carcinoma GPL81792535195680
GSE45364sarcomaGPL1685124375455115
GSE48088breast cancerGPL146132504708736
GSE48267colon cancerGPL1085024865442122
GSE51853lung cancerGPL734124903339131
GSE53870liver cancerGPL18118 -72
GSE53992liver cancerGPL181592501782846
GSE56183chordomaGPL14613 -12
GSE56350colorectal cancerGPL1674424921248104
GSE57370kidney cancerGPL167702567008366
GSE57555hepatocellular carcinomaGPL180442653841564
GSE57768skin cancerGPL17537 2576400048
GSE60978pancreatic cancerGPL151592557908689
GSE61438breast cancerGPL8179 -69
GSE62054thyroid cancerGPL8179-25
GSE63805lung cancerGPL184102613422362
GSE64318prostate cancerGPL82272608937554
GSE65819ovarian cancerGPL1976526017449121
GSE66274esophageal cancerGPL198232640982660
GSE67354gastric cancerGPL19952-10
GSE69580hepatocellular carcinomaGPL10850-10
GSE70574colorectal cancerGPL15018-16
GSE73487colon cancerGPL8786-113
GSE74190lung cancerGPL19622-136
GSE75630tonsil cancerGPL211982686758946
GSE76260prostate cancerGPL8179-64
GSE77380lung cancer, colorectal cancer, gastric cancerGPL16770-108
GSE80038breast cancerGPL18044-20
GSE24709lung cancerGPL9040-71
GSE25609colon cancerGPL8179-77
GSE27486lung cancerGPL114322302938045
GSE31309breast cancerGPL1413222242178105
GSE31568pancreatic cancer, melanoma, prostate cancer, ovarian cancer, gastric cancerGPL904021892151453
GSE31801ovarian cancerGPL817922235027121
GSE38419kidney cancerGPL90402287107042
GSE39845colon cancerGPL146132375863926
GSE41321retinoblastomaGPL148767234001116
GSE41922breast cancerGPL162242379790654
GSE48137kidney cancerGPL16770-102
GSE55993lung cancerGPL167702534486680
GSE59856pancreatic cancer, biliary tract cancer, colon cancer, gastric cancer, esophagus cancer, liver cancerGPL1894125706130571
GSE65071sarcomaGPL196312578429035
GSE71043esophageal cancerGPL18042-6
GSE37406pancreatic cancerGPL14903-24
GSE46188pancreatic adenocarcinomaGPL81792363565242
GSE50224esophageal cancerGPL8786-36
GSE53850lymphomaGPL16770-8
GSE62137chronic lymphocytic leukemiaGPL14767-44
GSE63159gastrointestinal stromal tumorGPL10656-34
GSE67257liver cancerGPL189412625237120
GSE74562pancreatic adenocarcinomaGPL14613-8
TCGA_BRCAbreast cancermiRNA-seq-1163
TCGA_KIRPkidney cancermiRNA-seq-324
TCGA_KIRCkidney cancermiRNA-seq-583
TCGA_KICHkidney cancermiRNA-seq-91
TCGA_LUADlung cancermiRNA-seq-555
TCGA_LUSClung cancermiRNA-seq-518
TCGA_UCECuterus cancermiRNA-seq-621
TCGA_COADcolon cancermiRNA-seq-450
TCGA_READcolorectal cancermiRNA-seq-161
TCGA_HNSChead and neck cancermiRNA-seq-564
TCGA_THCAthyroid cancermiRNA-seq-566
TCGA_PRADprostate cancermiRNA-seq-532
TCGA_STADgastric cancermiRNA-seq-475
TCGA_LIHCliver cancermiRNA-seq-420
TCGA_CESCcervical cancermiRNA-seq-304
TCGA_ACCadrenocortical tumormiRNA-seq-80
TCGA_PAADpancreatic cancermiRNA-seq-183
TCGA_ESCAesophageal cancermiRNA-seq-187
TCGA_CHOLliver cancermiRNA-seq-45
TCGA_SKCMskin cancermiRNA-seq-449
TCGA_BLCAbladder cancermiRNA-seq-426
TCGA_TGCTtesticular cancermiRNA-seq-149

 

3. Schematic Diagram for Cancer Location
Schematic Diagram for the loacation of major cancer types included in database



 

4. Data Analysis Flowchart
All differentially expressed miRNAs (DEMs) in this database are curated from public resources. The following work flow demonstrates the data collection process:



 

5. Database Search
dbDEMC allowes for database query by miRNA IDs, or sequence similarity search by BLAST



Search result page

 

6. Browse Cancer
You can select specific cancer type for browsing



Example of browse: Experiment list for particular cancer type

 

7. Experiment View
Lists of all experiments for all cancers



 

8. MiRNA Information Page
This page delineates the detailed information for each differentially expressed miRNAs.



Detailed expression information from limma are listed.

 

9. Meta-profiling
You can input miRNA IDs and view the Meta-profiling heatmap



Example of Meta-profiling heatmap

 

10. About Us
This database is hosted by Computational Systems Genomics Lab, Key Laboratory for Computational Biology of CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences

Contact Us:
Room #242
Shengli Building
320# Yueyang Road.
Shanghai 200031,
P. R. China
Email: Zhen Yang, Andrew E. Teschendorff